Sponsor: GERMAN MINISTRY EDUCATION & RESEARCH THROUGH JOHANNES GUTENBERG UNIVERSITY MAINZ
Gram-negative, pathogenic bacteria use the evolutionary conserved virulence factor Macrophage Infectivity Potentiator (Mip) for tissue penetration, dissemination and survival within human host cells. This project aims to develop non-immunosuppressive FK506 analogs as drug-like Mip inhibitors for the treatment of Mip-dependent pathogens.
Posting date: Tue, 09/10/2019
Award start date: Tue, 01/01/2019
Award end date: Thu, 12/31/2020
