 |
|
 |
Texas Tech University Health Science Center El Paso |
 | |
 | 915-215-4227 |
 | |
|
Rajkumar Lakshmanaswamy |
|
Texas Tech University Health Science Center El Paso |
My laboratory studies the physiological and molecular mechanisms involved in cancer prevention and progression. Our specific focus is on breast and pancreatic cancer. We use a broad array of basic and translational research approaches to address fundamental aspects of clinical significance by elucidating the vital pathways and mechanisms responsible for cancer growth and development. These approaches include biochemistry, cell biology, genomics, imaging, proteomics, molecular biology, and preclinical animal studies. We currently are investigating the mechanisms by which early pregnancy reduces lifetime risk of breast cancer. Further, we have developed a short-term hormone treatment, which mimics the protective effect of early pregnancy, and are using this approach to dissect the pathways by which short-term hormone treatment confers protection against breast cancer. We are also developing new treatment strategies against different cancers. We have successfully identified active compounds, which exhibit potent anticancer activities against both breast and pancreatic cancers, and are in the process of translating these experimental results into potential pre-clinical studies.
Content credit by:
Texas Tech University Health Science Center El Paso, source http://elpaso.ttuhsc.edu/research/biomedical/coe/cancer/faculty.aspx
