| A2: STRIOSOMAL MODELS OF DRUG USE AND COST PI: Alexander Friedman Co-PI: Travis Moschak, Laura O'Dell Sponsor: NIH - NATIONAL INSTITUTE ON DRUG ABUSE Biological Sciences Amount awarded: $2,840,059
Our understanding of the mechanistic underpinnings of drug consumption and craving has been greatly aided by the development of numerous computational models focused on these behaviors. However, most of these models ignore the role of cost. To this end, our proposal seeks to experimentally validate a novel computational neurobiological model of costly drug-taking behavior centered on the striosomes of the dorsomedial striatum (DMS). Posting date: Tue, 09/24/2024 Award start date: Mon, 07/01/2024 Award end date: Thu, 05/31/2029
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