Enhancements    

PRIMING PANCREATIC DUCTAL ADENOCARCINOMA USING BLOOD THINNERS TO SENSITIZE THE EFFICACY OF CHECKPOINT IMMUNOTHERAPY

PRIMING PANCREATIC DUCTAL ADENOCARCINOMA USING BLOOD THINNERS TO SENSITIZE THE EFFICACY OF CHECKPOINT IMMUNOTHERAPY
PI: Taslim Al-Hilal
Sponsor: NIH - NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
Pharmaceutical Sciences
Amount awarded: $1,507,750

Pancreatic cancers tend to develop small clots, called intratumoral clots, within their vascular network and interstitial milieu. This project will determine the effect of intratumoral fibrin clots on tumor microenvironment and immunity, and whether the use of blood thinners enhance the efficacy of immunotherapy in different subtypes of pancreatic cancer.

Posting date: Fri, 07/08/2022

Award start date: Tue, 07/05/2022
Award end date: Sun, 05/31/2026