Description:This patent application relates to the field of molecular imprinting. Embodiments further relate to the production of bio-inspired artificial antibodies with molecular imprinted silica particles.
Abstract:Methods and devices for molecular imprinting include a molecular imprinting synthesis and matching a physiological pH of a template utilized in the molecular imprinting synthesis to achieve molecular imprinting. Molecular imprinting can be achieved by matching the physiological pH of the template used in a molecular imprinting synthesis. Furthermore, electrostatic charges can be complementary matched to the template, by obtaining crystallographic data of a protein template. Particularly, positively and negatively charged amino acids can be counted and matched by an oppositely charged monomer. For hydrophobic amino acids, isoleucin, leucin, and valine amino acids are counted. Since not all hydrophobic amino acids are exposed, the hydrophobic amino acid and hydrophobic monomer ratio can be determined experimentally by varying ratios from 1:1 to 1:10.
Issue Date: 07/07/2020
Application Date: 12/01/2016
Post Date: 05/08/2018
UTEP Docket No: 2016-040
